Word: medawar
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...Nearly a year later, his worst fear may be coming true. If a virus, as Nobel laureate Peter Medawar described it, "is a piece of bad news wrapped in a protein," the past few weeks have had all the bad news the world can handle as avian influenza has broken out in Korea, Japan, Taiwan and Vietnam. Already, the disease appears to have jumped the species barrier, killing at least four people, and the virus is suspected of causing another 10 deaths. Asia has stared down avian-flu outbreaks before, notably in Hong Kong in 1997 when the city...
Beth Israel Deaconess Medical Center announced last week the formation of the first interdisciplinary transplant research center in New England. Anthony P. Monaco, Medawar Professor of Surgery at Harvard Medical School, will be the center’s first director...
Starzl acknowledges that this insight had also occurred to other researchers. Scientists, going back as far as 1960 Nobel prizewinner Peter Medawar, had come to recognize that tolerance was possible. If bone marrow, for instance, would only accept an interloping cell, the larger system would follow suit. The trouble was, the only way to achieve that was to kill off the body's entire current bone-marrow supply and replace it with another--a technique oncologists use as a last-ditch weapon to try to cleanse patients of such systemic cancers as leukemia and breast cancer...
...bone-marrow work and solid-organ transplant work have traditionally been two separate fields of medicine. "The big misconception," says Starzl, "was not realizing that the acceptance and tolerance of solid-organ grafts are due to the same mechanisms described by Medawar. There is a seamless work of transplantation immunology. It's so damn simple, it's crushing...
...suit, Anthony P. Monaco, Medawar professor of transplantation surgery, has said that the much-publicized merger of New England Deaconess and Beth Israel Hospitals may have contributed to his demotion...