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...first the drug worked well. Several days after a woman stopped taking it, she had what seemed like a normal but mild menstrual period. There were few side effects. But as the drug was further purified, Dr. Rock began to hear patients complain of too much "breakthrough bleeding" in mid-cycle. Analysis showed that the purified drug contained no detectable estrogen. Apparently estrogen, even in the most minute quantity, prevented some side effects, including unwanted bleeding. So when Chicago's G. D. Searle & Co., which had worked closely with Pincus and Rock, began making "the Pincus pills" as Enovid...

Author: /time Magazine | Title: Contraception: Freedom from Fear | 4/7/1967 | See Source »

...progestin (with a protective smidgen of estrogen added) for five or six days. The sequentials, like the combinations, tend to regularize the cycle, and most women who take them have an acceptably mild menstrual period...

Author: /time Magazine | Title: Contraception: Freedom from Fear | 4/7/1967 | See Source »

...that she suffered serious blood loss and near-shock, and needed transfusions. On the pill for six months, she now has "pink cheeks, regular periods, a good figure and has gained ten pounds." Wryly, a young woman in Miami says, "They've improved my complexion, done away with menstrual problems, eliminated worry, and I feel better physically. But they haven't straightened out my lousy love life...

Author: /time Magazine | Title: Contraception: Freedom from Fear | 4/7/1967 | See Source »

...serious. Dr. Connell is experimenting with a one-every-day "minipill." It consists of chlormadinone acetate, a synthetic that resembles progesterone and works in much the same way, but in doses only a quarter or half as big as those in even the smallest of the usual pills. Menstrual periods arrive regularly after a few months. The unwanted pregnancy rate is less than 2%, and a woman, knowing that she has to take the pill every day of the year, can forget about counting days...

Author: /time Magazine | Title: Contraception: Freedom from Fear | 4/7/1967 | See Source »

...still in the horse-and-buggy stage of contraception." Dr. Rock and Dr. Goldzieher have a more funda mental objection to present methods. All, they say, attack the problem from the wrong direction, trying to negate nature during most of a woman's possible average of about 400 menstrual cycles. The ideal would...

Author: /time Magazine | Title: Contraception: Freedom from Fear | 4/7/1967 | See Source »

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