Word: merck
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Dates: during 2000-2009
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...decision did not come as a complete surprise, since a similar and widely publicized vaccine developed by Merck failed to prevent infection or control HIV replication in a trial last year. At issue is the fact that researchers still don't know exactly how the body defends against HIV. Without critical knowledge of the precise immune factors, or correlates, that prevent infection, testing any vaccine candidate that functions by triggering immune defenses would be guesswork. That's why, Fauci says, he rejected the proposal to do a large trial, involving thousands of patients and numerous immune correlates. "What I will...
...trial that Fauci canceled last week was already a slimmed down version of the original 8,500-person study that government health officials had planned - until the Merck vaccine failed last fall. In a trial of 3,000 volunteers, Merck's vaccine appeared to increase risk of HIV infection, a phenomenon that researchers later attributed to the vaccine's delivery system - pieces of HIV were piggybacked onto a common cold virus and ferried to the body's immune cells. It turned out that the people who received the vaccine and who ended up with the highest rates of HIV infection...
...reach the 19-26 year olds, who dominate the Sex and the City fan base, the ad also will be shown in theaters playing movies like You Don't Mess with the Zohan and The Incredible Hulk raising speculation that young boys may be a target. Merck has acknowledged it is testing Gardasil on boys and young men who can carry the HPV virus with an eye to seeking FDA approval...
...latest in Merck's attempt to get the word out on its breakthrough vaccine. Last year, Merck was criticized for its association with the "Women in Government" lobbying campaign that drafted female state legislators in persuading their colleagues to adopt mandatory Gardasil vaccinations for young girls. The push caused a ruckus in some quarters and advocates like Texas Gov. Rick Perry, a conservative Republican, found himself under fire from his own supporters when he tried to mandate the vaccinations. His executive order was reversed by the state legislature...
...Merck has not said how much the movie ad buy cost the company, but it has acknowledged that it is about the same as last year's television buy for a spot dubbed "I chose..." which now can be seen on the company's website. The ad features mothers talking to their daughters about the need to address HPV concerns. Gardasil protects against four strains of the HPV virus, two of which cause 70% of cervical cancer cases. The other two strains can cause other HPV manifestations like genital warts. A study last year published in the New England Journal...