Word: merck
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Dates: during 2000-2009
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Plain old niacin--a B vitamin--may be better at unclogging arteries than an ingredient in Merck's multibillion-dollar cholesterol drugs Zetia and Vytorin, according to a recent study. It's the third trial in two years to question the pills' effectiveness. Patients are growing skittish: sales of both drugs fell to $4.56 billion in 2008, down 12% from the year before...
...have a population of patients who are protected against infection with HIV after inoculation; they can begin to analyze the patients' immune responses more closely to tease out the elusive factors that shielded them from HIV. That's more than the last promising vaccine provided. That candidate, made by Merck, not only failed to protect volunteers from infection but also seemed to increase their risk of contracting...
...have growing security divisions that track illegal medicine-trafficking and gather evidence to give to law-enforcement agencies to help them take action. Pfizer has also started experimenting with safer packaging. For example, all its Viagra blockbuster packs in the U.S. now have a radio-frequency-identification tag. Merck, meanwhile, is funding the distribution of minilabs to developing countries to improve detection of fake ingredients in drugs used to combat malaria, HIV and tuberculosis...
...Morton died after receiving GlaxoSmithKline's Cervarix, one of two vaccines designed to protect women from the human papillomavirus (HPV), a sexually transmitted infection linked to most cervical cancers. (American women receive Gardasil, an HPV vaccine manufactured by Merck.) Introduced last year, Cervarix is expected to cut deaths from cervical cancer in Britain by about 75% - or 650 deaths a year. So far, the vaccine has been given to 1.4 million women in Britain, and Morton's death is the first to be possibly linked to the shot. But there have also been less serious side effects in recipients. Britain...
...Africa suggest that male circumcision can cut the risk of HIV infection in men by up to 60%. Still, in a field that has been beset by a series of high-profile failures in the past 20 years - in 2007, for example, two international trials of a promising Merck vaccine in about 4,000 people were stopped early, and later analysis suggested that the vaccine may have increased people's risk of infection - the results of the Thai trial are a turning point. "In terms of where the vaccine world was even a few weeks ago, this is huge news...