Word: methodic
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Dates: during 1990-1999
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...That method suffers, however, because it takes 8-10 weeks on average, requires a relatively large sample, and the DNA has to be in good shape," Ferrara says. "A relatively large sample would be a blood stain the size of a half-dollar or a seminal fluid spot about the size of a dime...
There is another limitation to the RFLP method. "Each additional probing adds four or five days. With each additional probing, you have to wash the gel," Ferrara says. "After the third or fourth probing, you start to lose too much DNA to maintain accuracy...
However, the PCR method doesn't always provide numbers as small as RFLP...
...Some population geneticists felt that strict multiplication was not a sufficiently valid and conservative method because the size of the databases was considered too small to justify such large numbers (e.g., a database of 100 profiles leading to a calculation of a frequency of 1 in 100 million)," Ferrara says...
...Ferrara cautions that DNA profiling is not the only method that should be used to convict criminals...