Word: methylized
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Woodward started out with orthoto-luidine, an oily liquid extracted from coal tar, whose molecule has one six-carbon ring and one methyl (CH3) group. Step by step he attached more atoms, carefully choosing his reactions so that the atoms would fall in the proper places. After some 20 laboratory steps, his 22 Ibs. of original raw materials were reduced to 1/28 oz. of a genuine steroid. The compound's molecule has the steroid nucleus with an oxygen atom attached at one end and a carbome-thoxy (C02CH3) group at the other...
...chamber in operation, the felt under its cover is saturated with methyl (wood) alcohol. The alcohol vapor diffuses downward, becoming colder as it approaches the dry ice at the bottom. At some point in its downward motion it makes the air supersaturated. In this sensitive layer, cosmic rays or other fast-moving atomic particles leave trails that show up in a flashlight beam as brilliant white streaks...
Shadow & Substance. In Passaic, N.J., Joseph Gardella, arrested for drunken driving, explained that he had been repairing a tavern refrigerator, attributed his condition to fumes from the methyl chloride used as a cooling fluid...
...treatment of gout. It attracted the attention of cancer researchers because it is poisonous to living cells, impairs their power to divide. Most cancer workers were disappointed with colchicine and soon dropped it. But Dr. Hans Lettré of the University of Heidelberg persisted. He extracted N-methyl-colchicamid, a substance which proved to be ten times as powerful as colchicine itself in preventing the riotous multiplication of cells (a characteristic of cancer growth...
Fifty patients with breast cancer had been treated for three to four weeks with a salve containing N-methyl-colchicamid, Dr. Lettré told the Paris gathering. In the confusion of postwar Germany he could not keep tabs on them well enough to be sure that any had been free of the disease for five years (the minimum acceptable for a cancer "cure"), but several whose cancers disappeared had been free for three years...