Word: mice
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Dates: during 1950-1959
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...that occurs naturally in the blood, is one of the factors in immunity. Zymosan. a yeast product, raises the properdin level if given in small doses, but bigger doses make it fall sharply. Dr. William T. Bradner reported that after small shots of zymosan, 67% of transplanted cancers in mice disappeared, as against only 6% in untreated mice. But as the zymosan dose was increased, the cure rate plummeted...
...American Association for Cancer Research, meeting in Chicago, that the villain is not present in tobacco leaves in their natural, unburned state. His research team proved this by extracting tar from cigarette tobacco without burning it: the resulting substance produced virtually no cancers when painted on the backs of mice. But batches of the same tobacco were burned at varying temperatures, and the tars extracted. Tar from the lower-temperature-burning ranges (560° to 720° C.) produced few or no cancers. From 800° to 880° C. the number of cancers increased sharply. Conclusion: evidently, the cancer...
...Toronto's Chemist George Wright, the researchers washed tobacco in hot hexane, which dissolves the wax. They extracted the wax and burned it alone. The resulting tar proved to be at least ten times as cancer-potent as ordinary tar from whole tobacco: in five months all mice painted with a 5% solution from tests at 880° had papillomas (precursors of cancer), and 27% had full-blown cancer. The tar from the wax contained all the cancer agents now known to exist in small amounts in cigarette tar, but Dr. Wynder doubts that these substances are the only...
Animal tests support both explanations. Mice develop skin cancer (which resembles lung cancer because of the similarity of the tissues) after a single painting of methylcholanthrene outside the mouth, but they resist repeated paintings inside. However, if their saliva glands are removed and the mouth becomes ulcerated, they become susceptible to cancer. These results are consistent with observed cases of human mouth cancer. Such cases are rare among both smokers and betel-nut chewers with good teeth. But they are relatively common in individuals with jagged teeth or ill-fitting dentures that may have worn through the "physiological barrier...
Married. Betty Field, 39, actress of stage (Dream Girl) and screen (Of Mice and Men); and Edwin J. Lukas, 55, lawyer; she for the second time (her first: Playwright Elmer Rice), he for the third; in Manhattan...