Word: mice
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Dates: during 1980-1989
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...three, working independently, have been studying a group of genes that are intimately linked to the body's immune response. Snell, 76, of the Jackson Laboratory at Bar Harbor, Me., laid the groundwork with studies using mice. Attempting to transplant first tumor cells and then normal tissue, he discovered that the success of the operations depended on protein molecules on the surface of cells. These proteins, called antigens, have characteristic shapes and structures, but combinations differ from individual to individual. Snell found that the more antigens the subjects had in common, the more likely was the graft to take...
...individual what illnesses he is most likely to contract. Caracas-born Benacerraf, 59, who teaches at Harvard, has further defined the histocompatibility complex. He was intrigued by the variable nature of the immune response-the body's defense against such foreign invaders as viruses. In experiments with mice and guinea pigs, Benacerraf found that the genes that control the vigor of the immune response are part of the major histocompatibility complex...
Genetic jump from mice...
Just this past spring, scientists at U.C.L.A. announced that they had inserted foreign genes into the bone-marrow cells of mice, the first attempt at using new genetic-engineering techniques with living animals. But experiments on humans, experts said, were still years away. Not so. Last week it was disclosed that the great divide between research in mouse and in man had been quietly crossed...
...Quiet on the Western Front; after a long illness; in Los Angeles. Russian-born Milestone won his first Oscar for a 1927 war comedy called Two Arabian Knights. He also directed the 1931 version of The Front Page, starring Adolphe Menjou and Pat O'Brien, the 1940 Of Mice and Men, starring Burgess Meredith, and the 1962 remake of Mutiny on the Bounty, starring Marlon Brando...