Word: miceli
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Dates: during 2000-2009
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...always win. Miracle at St. Anna lugs its central narrative around much as Train does the statue head. And just as he rubs it for good luck, so Lee hopes the bonding of slow, sweet, huge Train and little Angelo - a kitschy mix of John Steinbeck's Of Mice and Men and Charlie Chaplin's The Kid - will propel audiences through the screeds on racism and the disasters...
...Lead author of the paper Qiao "Joe" Zhou, a post-doctoral fellow working in Melton's laboratory, said that finding the correct combination of the three transcription factors to reprogram the cell that makes gut enzymes in mice into a more useful pancreatic cell was the result of three years of repetitive lab work...
...Zhou said that systematic experiments narrowed down the transcription factors down to nine, which were then tested directly in the mice...
...newly created cells made insulin in diabetic mice, though they were not cured. But if the experiment's approach proves viable, it might lead to treatments like growing new heart cells after a heart attack or nerve cells to treat disorders like ALS, formerly Lou Gehrig's disease...
...researchers destroyed beta cells in mice with a poison, giving the mice diabetes. Then they injected the pancreas with viruses that slipped into the enzyme-making cells. These viruses delivered three genes that control the activity of other genes...