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What merits another look, some researchers believe, is a suite of chemicals used to make plastics. One is Bisphenol A, or BPA. Like DDE and PCBs, it is a chemical cousin of estrogen's, and it has been shown to affect the reproductive systems of lab mice. Another category of plastics ingredients, phthalates, may have played a role in a rash of cases of very early puberty in Puerto Rico back in the 1980s, with girls as young as 2 growing breasts and pubic hair. And while no cause has yet been determined, a study published last month suggests that...

Author: /time Magazine | Title: Teens Before Their Time | 10/30/2000 | See Source »

Earlier this year Medical School Professor Frank McKeon genetically engineered mice that lack p73 to see whether they would develop cancer, just as mice that lack p53 do. The mice had "profound" defects in their metabolism and their nervous systems, but no tumors...

Author: By Joshua E. Gewolb, CRIMSON STAFF WRITER | Title: Harvard Cancer Researchers Probe Cell Suicide | 10/26/2000 | See Source »

...view radically changed in the late 1950s when Swedish pharmacologist Arvid Carlsson brought dopamine out of the shadows. First Carlsson established that the areas of the brain known as the basal ganglia contained very high levels of dopamine. Then he administered a drug that lowered those concentrations in laboratory mice. Soon the mice began to stagger and reel, losing control of their voluntary movements...

Author: /time Magazine | Title: Medicine: Not So Dopey Dopamine | 10/23/2000 | See Source »

Carlsson's mice, in other words, resembled human patients with Parkinson's disease--and L-dopa, the dopamine-boosting compound he used to restore normality to the mice, soon emerged as the frontline treatment for Parkinson...

Author: /time Magazine | Title: Medicine: Not So Dopey Dopamine | 10/23/2000 | See Source »

...role insulin plays in aging in mice is not yet known, but when mice are placed on a restricted diet, which lowers their insulin levels, they live longer...

Author: By Joshua E. Gewolb, CRIMSON STAFF WRITER | Title: Harvard Prof. Finds Brain Regulates Aging | 10/20/2000 | See Source »

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