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...become obvious until 1963, when Canadian researchers Ernest McCulloch and James Till first proved the existence of stem cells, in the blood. These cells possess the ability to divide and create progeny - some of which will eventually expire, others that are self-renewing. The pair irradiated mice, destroying their immune cells. They then injected versatile bone-marrow cells into the animals' spleens and were surprised to see a ball of cells grow from each injection site. Each mass turned out to have emerged from a single stem cell, which in turn generated new blood cells...

Author: /time Magazine | Title: Stem-Cell Research: The Quest Resumes | 1/29/2009 | See Source »

...Melton's team has already replaced two of the genes with chemicals, and he anticipates that the remaining ones will be swapped out in a few years. There are also hints that the iPS cells' short-circuited development makes them different in some ways from their embryonic counterparts. In mice, embryonic stem cells can generate a new mouse clone; iPS cells from the animals have so far stopped short of the same feat, aborting in midgestation, suggesting that some development cues may be missing. "It certainly makes me cautious," says Eggan...

Author: /time Magazine | Title: Stem-Cell Research: The Quest Resumes | 1/29/2009 | See Source »

...artistic director of Boston Ballet, has not ventured into the common practice, as of late, of creating some innovative, delirious hallucinogen with no ties to the original, beautiful children’s tale that was E.T.A. Hoffman’s “The Nutcracker and the King of Mice.” In his production, which runs at the Boston Opera House through Dec. 28, Nissinen sticks, for the most part, to the tried and true formula, and the few innovations he does risk add charm to a story that will never suffer from superfluity.Nissinen surely took inspiration...

Author: By Erica A. Sheftman, CONTRIBUTING WRITER | Title: A Classic Holiday Ballet | 1/22/2009 | See Source »

...establishment hated Wyeth for much of his career. He was a regionalist and a realist when the vogue was abstract expressionism, a plainspoken farmer among chain smoking wildmen. He was the country mouse; they were the city mice. He had nothing new to show them, and they had no time...

Author: By Jillian J. Goodman | Title: Anatomy of America | 1/20/2009 | See Source »

...bodies tend to store weight around their abdomens. Researchers already knew abdominal obesity came with a higher risk of diabetes and cardiovascular disease. What Kahn wanted to know was what would happen if the fat from the two areas was switched. So he injected lower-body fat from mice into their abdomens. “What we found was that moving the fat under the skin and hips...actually improved metabolism,” Kahn said in an interview. Mice with the transplanted fat lost weight, had lower insulin levels, and had better insulin sensitivity. Kahn had found that...

Author: By Lingbo Li, CRIMSON STAFF WRITER | Title: Study: Big Behinds May Benefit Health | 1/7/2009 | See Source »

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