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...Over the past 60 years, scientists have figured out what works best in what models. The vast majority of animal testing [today] is in rodents, either rats or mice. Rodents, particularly mice, have very short life spans, so you can see how a compound would react in a young animal, then in the same geriatric animal, and then in the next-generation animal, all in a time frame that is reasonable. Then if a product or a compound is determined to be safe in a rodent, another species is used. For example, if it's a neurological compound, oftentimes...

Author: /time Magazine | Title: How Much Does Animal Testing Tell Us? | 6/17/2008 | See Source »

...week goes by without news of a lab breakthrough using rats or mice. But of all the promising medical interventions that make it to animal trials, only a fraction seem to translate into major breakthroughs for humans. Frankie Trull, president of the non-profit Foundation for Biomedical Research (a promoter of responsible animal testing), explains the promise and the pitfalls of pre-clinical trials...

Author: /time Magazine | Title: How Much Does Animal Testing Tell Us? | 6/17/2008 | See Source »

...course, science is always making progress. You read a lot about these very special rodents, animals we call "transgenic animals." [That means] if you're studying diabetes, the mice have diabetes, so you can go right to specific disease targets in a much more expeditious way that you could in the old days. In the old days you just hoped they got diabetes. Also, as the scientific community is understanding more and more about the genome, whether it's the human genome or the fruit fly genome, they're better able to identify gene markers, to target them and start...

Author: /time Magazine | Title: How Much Does Animal Testing Tell Us? | 6/17/2008 | See Source »

...WINEHOUSE and Pete Doherty play with box of newborn mice on YouTube. So things are obviously going just fine for them...

Author: /time Magazine | Title: Pop Chart | 5/22/2008 | See Source »

...Rats had to walk balance beams and stay upright during a log-rolling task. Those raised on special blueberry rat chow did significantly better than those that were not, leading Joseph to conclude that "blueberries were actually able to reverse motor deficits in these aging animals." More remarkably, when mice that had been genetically altered to express Alzheimer's were put on the blueberry diet, they did not experience memory loss. Joseph's research has shown some similar benefits from walnuts, which contain alpha-linolenic acid, an essential omega-3 fatty acid...

Author: /time Magazine | Title: Memory: Forgetting Is the New Normal | 5/8/2008 | See Source »

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