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Melanoma, a lethal human skin cancer, can be suppressed in mice by targeting cancer stem cells, according to a report from several Harvard authors in the Jan. 17 issue of Nature magazine...

Author: By Kevin C. Leu, CRIMSON STAFF WRITER | Title: Harvard Scientists Test Stem Cells in Fight Against Melanoma | 2/7/2008 | See Source »

After injecting melanoma-infected mice with antibodies that bind specifically to ABCB5, Frank and his colleagues found that tumors in eight of the 11 test subjects were gone...

Author: By Kevin C. Leu, CRIMSON STAFF WRITER | Title: Harvard Scientists Test Stem Cells in Fight Against Melanoma | 2/7/2008 | See Source »

...comparison, all 28 mice who were not given the antibodies developed new tumors as the cancer cells spread to other parts of their bodies...

Author: By Kevin C. Leu, CRIMSON STAFF WRITER | Title: Harvard Scientists Test Stem Cells in Fight Against Melanoma | 2/7/2008 | See Source »

...Frank and his colleagues, the next phase is to bring the research from mice to humans...

Author: By Kevin C. Leu, CRIMSON STAFF WRITER | Title: Harvard Scientists Test Stem Cells in Fight Against Melanoma | 2/7/2008 | See Source »

...prophylaxis) studies are conducted in animals, they often give people a "false sense of protection and lead to less condom usage," says Bowers, particularly among highly sexually active individuals. Last spring, following the buzz over studies of tenofovir and emtricitabine, the same drug combo used in the recent Texas mice study, in preventing transmission of SIV (the primate-specific cousin of HIV) in macaque monkeys, Bowers was compelled to respond in his column in HIV Plus magazine, warning that "society once again is moving ahead of science. ... This is definitely not the time to be leaving condoms behind...

Author: /time Magazine | Title: Self-Medicating With AIDS Drugs | 1/28/2008 | See Source »

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