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...receptors (the Glu is for glutamate, a key signaling agent in the brain). They reasoned that it would be possible to correct the excesses of Fragile X by blocking these receptors, which act as accelerators of protein production. To test this idea, the researchers produced a special breed of mice that had the Fragile X trait but only half the normal number of mGluR5 receptors. The result, explains Bear: "We were able to correct the excesses [of Fragile X], taking our foot off the accelerator...

Author: /time Magazine | Title: A New Approach to Correcting Autism | 12/19/2007 | See Source »

What was especially remarkable was the number of ways the intervention reversed Fragile X symptoms. The specially bred mice had fewer seizures, more normal brain structure, a more typical rate of body growth and they performed better on a learning task than mice with uncorrected Fragile X. The experiment suggests that treating Fragile X with a drug that inhibits mGluR5 receptors could have similarly healing effects...

Author: /time Magazine | Title: A New Approach to Correcting Autism | 12/19/2007 | See Source »

...percent happy about this because the place that we are living in is unlivable,” she said. “The place that I’m living is filled with mice and diseases...

Author: By Laura A. Moore, CRIMSON STAFF WRITER | Title: University Acquires Allston Land | 11/30/2007 | See Source »

...percent happy about this because the place that we are living in is unlivable,” she said. “The place that I’m living is filled with mice and diseases...

Author: By Laura A. Moore, CRIMSON STAFF WRITER | Title: University Acquires Allston Land | 11/29/2007 | See Source »

...Portland successfully nurtured a line of embryonic stem cells from monkeys using the same process that created Dolly. The feat brings us one step closer to being able to generate patient-specific stem cells to treat diseases in human patients, since primates are evolutionarily closer to humans than mice, in whom the process was tested...

Author: /time Magazine | Title: A Breakthrough on Stem Cells | 11/20/2007 | See Source »

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