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...could already see by looking at the intestine under the microscope that bad things were happening by three, three-and-a-half weeks of age,” said Glimcher, who authored the study. “A hundred percent of the mice got the disease—a very aggressive disease. We pretty much had to euthanize the mice by the time they were 12 weeks...

Author: By Clifford M. Marks, CRIMSON STAFF WRITER | Title: Lab Mice Point to Diarrhea Cause | 10/5/2007 | See Source »

When a family of genetically modified mice started dying in a Harvard School of Public Health lab, researchers were puzzled...

Author: By Clifford M. Marks, CRIMSON STAFF WRITER | Title: Lab Mice Point to Diarrhea Cause | 10/5/2007 | See Source »

...come you have so many cages of these mice breeding but don’t seem to have enough mice to do experiments?” Laurie Glimcher, a professor of immunology at the School of Public Health, recalled asking...

Author: By Clifford M. Marks, CRIMSON STAFF WRITER | Title: Lab Mice Point to Diarrhea Cause | 10/5/2007 | See Source »

...mice had been genetically altered to lack a protein called ‘T-bet,’ which the researchers now believe acts as a ‘peacekeeper,’ preventing harmful bacteria from breaching the single layer of cells which protects the rest of the body from the microbe-infested...

Author: By Clifford M. Marks, CRIMSON STAFF WRITER | Title: Lab Mice Point to Diarrhea Cause | 10/5/2007 | See Source »

...some experts, such as Boston College's Thomas Seyfried, say it's still a remarkable achievement. Seyfried has long called for clinical trials of low-carb, high-fat diets against cancer, and has been trying to push research in the field with animal studies: His results suggest that mice survive cancers, including brain cancer, much longer when put on high-fat diets, even longer when the diets are also calorie-restricted. "Clinical studies are highly warranted," he says, attributing the lack of human studies to the medical establishment, which he feels is single-minded in its approach to treatment...

Author: /time Magazine | Title: Can a High-Fat Diet Beat Cancer? | 9/17/2007 | See Source »

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