Word: miceli
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Nose drops developed by Harvard Medical School researchers have impeded the development of Alzheimer’s disease in mice, and an anti-Alzheimer’s nasal spray for humans could be on the horizon. While plaques made up of beta-amyloid proteins accumulate in the brains of Alzheimer’s sufferers, the new vaccine allows the immune system to produce antibodies that fight these proteins. In tests that have are detailed in the latest issue of the Journal of Neuroscience, the vaccine significantly diminished plaques on the brains of treated mice. Similar tests on human subjects began...
...very heterogeneous disorder and it has many different causes,” he said. “This may be one part of the puzzle for one particular kind of depression.” Ardayfio and his advisor, Associate Professor of Psychiatry Kwang-Soo Kim, tested three groups of mice on a standard anxiety-level test. The mice were placed in a darkened chamber, allowed to acclimatize themselves, and were then allowed to explore another brightly lit chamber. Ardayfio and Kim found that, while normal mice readily explored the new area, mice which had received long-term doses...
...idea that the same process could be at work in cancer originated with leukemia researchers. In a series of studies in the 1990s, scientists began taking leukemia cells from human patients, separating out fractions of those cells and putting them into mice specially bred to tolerate human implants. Some of the cell fractions developed into tumors in the animals, while others did not. That was the first proof that the cells in a cancer were not homogeneous. Some cells were more dangerous than others...
...edge, working from the knowledge of blood stem cells they have been building since the 1940s. Dick's group in Toronto was the first to identify a protein, CD34, as a potential screen for leukemia stem cells. He showed that tumor cells with plenty of CD34, when injected into mice, flowered into cancerous growths. Leukemia cells without the protein, by contrast, did nothing...
Because characteristics like limb development are governed by powerful families of genes known as Hox genes, the fishapod's curious mix of features intrigues developmental biologists as much as it does paleontologists. Recent experiments on mice by University of Geneva geneticist Denis Duboule and his colleagues, for example, show that Hox genes control limb development in two stages. "Even though the same genes are involved," says Duboule, "separate processes govern the development of arms and legs and the development of hands and feet...