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...Tarjei S. Mikkelsen, a graduate student at the Harvard-MIT Division of Health Sciences and Technology (HST) and one of the leaders of the research project, said that researchers were surprised that the sequences that humans had in common with dogs were the same sequences that humans shared with mice. The similarities between the three mammalian species allow researchers to identify the most biologically important genetic elements in humans, Mikkelsen said. “This is a significant step toward assembling a complete parts list for the human genome,” he added. Mikkelsen and fellow researchers have found...

Author: By Sadia Ahsanuddin, CONTRIBUTING WRITER | Title: Man’s Best Friend Has Similar Genes Too | 12/13/2005 | See Source »

...already won. What more was there for me to do?” Nichols says. Study, it seems. “Yeah, I’m a badass motherfucker who studies astrophysics,” Nichols deadpans. He researches at an MIT lab, where his latest project involves shipping mice to Mars. He begins to demonstrate the basic physics governing astronomy using his dinner plate: “Were I to spin it like this”—he stops, interrupting himself, and grabs a fork—“better yet, if I sent this fork...

Author: By Sherri Y. Geng, CONTRIBUTING WRITER | Title: The Beer-Guzzling Astrophysicist | 12/7/2005 | See Source »

CLONING Scientists had cloned sheep, pigs, cattle, mice, rabbits, horses and cats but, until this year, never a dog. Man's best friend, it turns out, is extremely difficult to duplicate. It was Woo Suk Hwang and his team at Seoul National University who finally succeeded in turning a single cell from the ear of an Afghan hound into a genetically identical puppy. Hwang was back in the news last week when he admitted lying about the source of some of the human eggs used in an earlier stem-cell experiment. Nevertheless, many scientists suspect the techniques Hwang perfected...

Author: /time Magazine | Title: A-Z Guide to the Year in Medicine | 11/27/2005 | See Source »

Harvard affiliates and other scientists have identified a gene in mice that could lead to new treatments for anxiety disorders in humans. According to a study published in last week’s issue of the scientific journal “Cell,” a mutation in a single gene that controls production of the protein stathmin can embolden mice to make them more willing to explore and less likely to fear painful or dangerous stimuli. Vadim Y. Bolshakov—director of McLean Hospital’s Cellular Neurobiology Laboratory and associate professor of psychiatry at Harvard Medical...

Author: By Abi O. Orisamolu, CONTRIBUTING WRITER | Title: Mutant Mouse Gene Quells Fear | 11/23/2005 | See Source »

...kind of therapy - and safer than cells derived from bone or muscle tissue. "The results are promising and we don't see the complications that we see with other cell types," he says. Piero Anversa, a heart expert at New York Medical College who pioneered a similar procedure in mice, agrees that placing blood-derived stem cells in the heart and arteries poses "no danger for the patients," although he says that the therapy still hasn't been proven effective. In clinical trials reported in U.S. medical journals, Patel's procedures have improved the heart's pumping ability...

Author: /time Magazine | Title: Take Heart | 11/13/2005 | See Source »

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