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...first opened up animal genomes: fly geneticists found a small group of genes called the hox genes that seemed to set out the body plan of the fly during its early development--telling it roughly where to put the head, legs, wings and so on. But then colleagues studying mice found the same hox genes, in the same order, doing the same job in Mickey's world--telling the mouse where to put its various parts. And when scientists looked in our genome, they found hox genes there...

Author: /time Magazine | Title: What Makes You Who You Are | 6/2/2003 | See Source »

Small changes in the promoter can have profound effects on the expression of a hox gene. For example, mice have short necks and long bodies; chickens have long necks and short bodies. If you count the vertebrae in the necks and thoraxes of mice and chickens, you will find that a mouse has seven neck and 13 thoracic vertebrae, a chicken 14 and seven, respectively. The source of this difference lies in the promoter attached to HoxC8, a hox gene that helps shape the thorax of the body. The promoter is a 200-letter paragraph...

Author: /time Magazine | Title: What Makes You Who You Are | 6/2/2003 | See Source »

...SARS coronavirus is the 14th known member of a family of viruses named for their distinctive, crown-like shape. Eleven exist in animals?dogs, cats, rats, mice, pigs, cows, rabbits and turkeys?and two infect the human race, in which they produce that most familiar of all ailments: the common cold. Scientists, who have long suspected that humans were originally infected with common-cold coronaviruses by contact with an unknown animal many centuries ago, had already posited a possible animal connection in the current outbreak. The fact that many of the initial victims in China's southern province of Guangdong...

Author: /time Magazine | Title: Scouring the Market for SARS | 5/26/2003 | See Source »

...book Of Mice and Men, by John Steinbeck, is full of themes—as many themes as there are rabbits in a thriving den, and as many sub-themes and tunnels between themes as in the den itself. Undergirding this abundance is the book’s central Theme, that of (the) rabbit(s). It can fairly be said, with remarkable brashness and deceptively little initial qualification, that John Steinbeck’s Of Mice and Men is all about rabbits. Rabbits are more than just characters in the novel: they in some sense are the novel...

Author: By Madeleine S. Elfenbein, | Title: Old Rabbits Die Hard | 5/19/2003 | See Source »

...about to get much more complex now that scientists have turned stem cells from mouse embryos into viable eggs. The report in Science set researchers' imaginations ablaze. Could this technique provide an endless supply of human eggs? And since scientists turned cells from both female and male mice into eggs, could it overturn traditional notions of parenthood? Could males make egg cells? Could gay couples produce genetic offspring? So far, the research holds promise only for gay mice...

Author: /time Magazine | Title: Health Briefs: Can Men Make Eggs? | 5/12/2003 | See Source »

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