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...could for years only be guessed at. The first big breakthrough occurred in 1995, when the Rockefeller's Friedman stunned the scientific world by announcing that he and his colleagues had discovered a hormone produced by fat cells that actually caused fat to melt away, at least in laboratory mice. Genetically engineered mice that lacked the gene for making this hormone developed ravenous appetites and became grossly obese. When these same mice were injected with the missing hormone, they shrugged off a third of the weight they had gained. The researchers dubbed the new hormone leptin, after leptos, which...

Author: /time Magazine | Title: Cracking the Fat Riddle | 9/2/2002 | See Source »

Intriguingly, some people seem to be more efficient at thermogenesis than others. Researchers led by Dr. Bradford Lowell at Beth Israel Deaconess Medical Center in Boston last month pinpointed three genes that may account for at least some of that variation. Mice that lack the genes, they reported in Science, grow grossly obese when fed a high-calorie diet enriched with fat and sucrose. By contrast, normal mice fed the same diet gain very modest amounts of weight...

Author: /time Magazine | Title: Cracking the Fat Riddle | 9/2/2002 | See Source »

...Mice and Cell Phones You can say a lot of bad things about cell phones. For starters, they're annoying, expensive, and poor quality. But here's one bit of good news: They may not foster tumor growth. In a study of 1,600 mice conducted at the Adelaide-based Institute of Medical and Veterinary Science in Australia, researchers concluded that radio waves from cell phones do not trigger tumor growth...

Author: /time Magazine | Title: U.S. Considered Suicide Interceptors | 8/30/2002 | See Source »

After all, we have been down this road before. When scientists reported in the mid-1990s that the absence of a hormone called leptin triggered the development of some very fat mice, it seemed that a cure for obesity was finally at hand. If these fat mice didn't make enough leptin, the reasoning went, then maybe fat people didn't make enough either. Would giving them leptin make them thin? The logic was so compelling that the pharmaceuticals firm Amgen reportedly paid tens of millions of dollars for development rights. It turned out, however, that most fat people...

Author: /time Magazine | Title: The Secret of Feeling Full | 8/19/2002 | See Source »

...University, pointing to the number of field animals inadvertently killed during crop production and harvest. One study showed that simply mowing an alfalfa field caused a 50% reduction in the gray-tailed vole population. Mortality rates increase with each pass of the tractor to plow, plant and harvest. Rabbits, mice and pheasants, he says, are the indiscriminate "collateral damage" of row crops and the grain industry...

Author: /time Magazine | Title: Should We All Be Vegetarians? | 7/15/2002 | See Source »

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