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...called epidermal growth factor (EGF). It's a close cousin to HER2, and Mendelsohn and his team know that it is present in a huge variety of tumors; two-thirds of all cancer types, in fact, are blanketed with EGF receptors. In 1984 Mendelsohn and his team showed in mice that blocking the EGF receptor with a growth-factor decoy prevented a cell from growing and dividing...

Author: /time Magazine | Title: New Hope For Cancer | 5/28/2001 | See Source »

...thanks to new research out of Harvard University and the Mount Sinai School of Medicine, I may have an excuse for what I euphemistically refer to as my "little sugar problem." In two separate studies, scientists found a gene in mice they believe is responsible for craving sweetness - and it may also exist in humans. If these findings, detailed in the May issue of Nature Genetics, hold true for people, they could help explain why some of us are riveted by a box of saltwater taffy while others can simply turn away...

Author: /time Magazine | Title: Is Sweetness in the Genes of the Beholder? | 4/23/2001 | See Source »

...gene, called T1R3, has not yet been proven to be the elusive "sweet tooth gene," but scientists plan to test their findings by implanting the gene into mice who seem to lack an interest in sugar water and see if they can stimulate a sweet tooth response. (I think scientists might get a better response if they used a nice chocolate bar, but that's just...

Author: /time Magazine | Title: Is Sweetness in the Genes of the Beholder? | 4/23/2001 | See Source »

Even before J.K. Rowling's Harry Potter, British writer Brian Jacques (pronounced Jakes) was selling millions of 400-page books to spellbound children and parents. His 14-book Redwall series, featuring heroic medieval rabbits and mice battling evil rats, has more than 5 million books in print. Jacques, 61, hosts an animated public television series based on Redwall that begins airing in the U.S. this month, and has a new, eagerly awaited book, Castaways of the Flying Dutchman, which chronicles the stirring adventures of young Ben and Ned, his faithful black Labrador. TIME spent a morning with Jacques...

Author: /time Magazine | Title: Families: Riding The Waves | 4/16/2001 | See Source »

...Best of all, the enzyme-deprived mice were in robust health, producing baby mice with no problem and generally acting like any other mouse. That's great news for obesity researchers, who speculate that scientists may figure out a way to inhibit the fat-metabolizing enzyme in humans and control weight gain. And such a pill would be nothing short of a miracle for many struggling to shed dangerous excess pounds...

Author: /time Magazine | Title: Eat Yourself Thin | 3/29/2001 | See Source »

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