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Karlson dipped into his tiny supply of pure ecdysone and sent a five-milligram test sample to Ulrich Clever, a young biochemist at the Max Planck Institute in Tübingen. Clever had been investigating the appearance of puffy swellings on microscopic, DNA-carrying chromosomes in the salivary glands of fly larvae. The puffs appear just before the larvae mature and change into pupae, and the tiny swelling seems to cause the metamorphosis. Karlson wondered how ecdysone would affect that transformation...

Author: /time Magazine | Title: Genetics: How Nature Reads the Code | 11/15/1963 | See Source »

...patient get? Dr. Durovic says he brought less than a -teaspoonful-two grams-of the whitish powder from Argentina. This would mean that" it" had been extracted from 2,000 horses (costly, because the horses are killed in the process), as Durovic says he gets only about one milligram per horse. And the human dose of Krebiozen is so fantastically minute-only 1/100 of a milligram-that two grams would be enough for 200,000 doses. Durovic has recently announced making his first U.S. batch of 200 mg. from 200 horses...

Author: /time Magazine | Title: Medicine: Cancer & Krebiozen | 10/10/1960 | See Source »

...average caponette weighs 2,500 gm. (about 5½ Ibs.). So, by the FDA's top-hazard figures, a roast-caponette fancier would get only a minute fraction of a milligram of stilbestrol if he ate all the skin fat and liver. Medical doses of stilbestrol for human patients cover a wide range beginning at .1 mg. daily, but often run to 15 mg. daily, and may go as high...

Author: /time Magazine | Title: Medicine: Hormones & Chickens | 12/21/1959 | See Source »

...operating table, the heart of the baby boy began fibrillating-quivering ineffectually. His surgeons quickly restored blood circulation by manual massage, but that solved nothing. Nearly an hour later, they tried something entirely new: a small (10-milligram) dose of tetraethylammonium chloride injected directly into the child's coronary artery system. Almost immediately the heart began beating regularly again...

Author: /time Magazine | Title: Medicine: Safer Heart Operations | 10/6/1958 | See Source »

...smoking with lung cancer and by congressional charges that many filters actually filter very little (TIME, March 3), tobaccomen are quietly reducing nicotine and tars in cigarettes. Last week Consumer Reports, whose March 1957 tests played a large part in the congressional blast, reported results of latest tests, showing milligram declines in the last year. Those brands lowest in content...

Author: /time Magazine | Title: TOBACCO: Tar Down | 3/31/1958 | See Source »

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