Word: minoxidil
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Dates: during 1980-1989
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...Administration approved a prescription medicine that increases hair growth in some men whose hair is thinning on top but not completely gone. Marketed by the Upjohn Co. under the trade name Rogaine, it is the first product ever cleared by federal regulators for treating hair loss. Its key ingredient: minoxidil, a highly touted drug that, in tablet form, had already been approved to treat high blood pressure. Only by accident did researchers discover that minoxidil could also regrow hair. Anticipating a vast new market for the drug, Upjohn developed a liquid version and began testing it on bald heads. After...
...results are only one in five, a large investment for a reasonably low chance of real cosmetic benefit." Moreover, if the applications are discontinued, the new hair disappears within a few months and balding continues at its previous pace. Says New York Dermatologist Stephen Kurtin: "The biggest resistance to minoxidil is not that the results may be only fair, but that it is a lifetime commitment...
...While minoxidil appears to be safe, the FDA advises patients to get a thorough physical before taking it and then see their doctors periodically. One reason: those who have cardiovascular disease and who also absorb the drug more easily than others may be at risk of developing an irregular heartbeat, among other side effects. None of the test subjects have suffered such serious problems, however, although some have developed such minor complaints as itching, scaling and blistering of the scalp...
...turnout at last week's Food and Drug Administration hearing was unusually large, with many a gleaming pate to be seen in the crowd. The subject of discussion: minoxidil (brand name: Rogaine), the Upjohn Co. preparation that has given new hope to the balding and new vigor to the company's stock. Originally marketed as a treatment for hypertension, minoxidil, in liquid form, was found by 48% of the men in an Upjohn study to produce "moderate-to- dense" hair growth if applied twice daily. Dermatologist Robert Stern, who headed an FDA advisory panel reviewing the drug, finds this...
...Regaine will not come cheap; a year's treatment with the prescription-only lotion may run around $1,000. But no one doubts there will be plenty of takers. Some resourceful men are creating a moonshine tonic on their own. The key ingredient: mashed hypertension pills, containing--what else?--minoxidil...