Word: model
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Dates: during 2000-2009
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...Over the past 60 years, scientists have figured out what works best in what models. The vast majority of animal testing [today] is in rodents, either rats or mice. Rodents, particularly mice, have very short life spans, so you can see how a compound would react in a young animal, then in the same geriatric animal, and then in the next-generation animal, all in a time frame that is reasonable. Then if a product or a compound is determined to be safe in a rodent, another species is used. For example, if it's a neurological compound, oftentimes...
...There is no question that, despite the excellent results that come out of lots of preclinical trials, the human is the ultimate animal model - and sometimes a potential downside to a new compound is not identified until it gets to a human. We often hear you can't give aspirin to cats because it's toxic to them, or you shouldn't give chocolate to dogs. Chocolate, which is very safe in humans, is not safe in dogs. But when you go back and look at how many compounds fail before they ever get to humans, [it's clear] animals...
...hoteliers such as Starwood's Brian McGuinness are on to you. Pulling up to a warehouse in an anonymous Hawthorne, N.Y., industrial park, McGuinness, head of Starwood's new line of hotels, Aloft, is eager to show off the full-scale model of the group's newest brand, a 136-room hotel with an average rate of $150 per night. Leading the way, McGuinness stops before a brightly lit entrance. A waterfall cascades down a wall, replete with the soothing sounds of a babbling brook, "to wash away troubles," he explains as he passes through the second set of doors...
Nikki Blonsky is exactly the role model most parents dream of for their kids. She's happy, she's successful, she's overcome obstacles--no wonder her young fans adore her. She's also overweight--by some measures very overweight--in a culture that fetishizes thin...
...cars the first year; GM alone produces about 300,000 cars a month. Perhaps the Aptera will be used as part of a light-rail system where the commuter will hop into a small car waiting at the train station. Or perhaps the Aptera will serve as a model for cars of the future: lightweight, great gas mileage, and loaded with computer controls...