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...million trial of a novel combination of two older vaccines was the first to show protection against HIV infection. The results of the trial, which involved more than 16,000 volunteers, suggested that the vaccine was 31% effective at preventing infection among those who were inoculated. It was a modest outcome, given that behavior-based prevention methods, like condom use, can be equally if not more effective. The volunteers were also largely heterosexual and monogamous, putting them at low-to-moderate risk for HIV infection - rather than high-risk, like intravenous drug users - and prompting questions about how impressive...

Author: /time Magazine | Title: TIME's Top 10 Medical Breakthroughs of 2009 | 12/8/2009 | See Source »

...even some of the more modest predictions about Jacob Zuma's rise to power had been correct, South Africa would be an empty, corrupt dictatorship by now. Back in 2006, South African memoirist Rian Malan ended his dismal assessment of the nation's prospects ("Not civil war, but sad decay") in British magazine the Spectator by asking: "Anyone want a house here?" A year ago, Archbishop Emeritus Desmond Tutu said he was "deeply saddened" when Zuma staged a party coup against his predecessor Thabo Mbeki, "deeply disturbed" that both had used institutions of state in their struggle and warned that...

Author: /time Magazine | Title: Could Zuma Be What South Africa Needs? | 12/7/2009 | See Source »

...older than New Moon's teen-vixen pack, took its time catching up with the movie's eloquent word of mouth. But no one need feel sorry for New Moon. Its domestic gross, $255.6 million, is nearly double that of The Blind Side's $129.3 million. And with a modest budget of $50 million, a worldwide cumulative gross of $570 million and two or three more Twilight movies in the offing, the franchise has a lot of bite left in it. (Read "New Moon Review: Team Jacob Ascending...

Author: /time Magazine | Title: Box-Office Weekend: Blind Side Sacks New Moon | 12/6/2009 | See Source »

...troops to the front, hoping to hold the line enough that Afghan forces can be built up to eventually take over the mission from the U.S. It may sound like a limited goal, after the sweeping visions of democracy promised during the Bush years. But even that relatively modest strategy is based on some very questionable assumptions. (See a slide show of the war in Afghanistan up close...

Author: /time Magazine | Title: Five Flawed Assumptions of Obama's Afghan Surge | 12/6/2009 | See Source »

...first districts to adopt school turnaround plans that mimic those favored by the Education Department. On Nov. 30, the city's school board approved measures that would have the district employ each of the four turnaround strategies at various schools across the district. "We can't pretend that modest changes to the status quo are going to deliver significantly different results," says Denver superintendent Tom Boasberg, who has been on the job for a year since replacing former superintendent (now U.S. Senator) Michael Bennet...

Author: /time Magazine | Title: Calling Out America's Worst Schools: A $3.5 Billion Plan | 12/4/2009 | See Source »

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