Word: modestly
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Dates: during 1990-1999
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...didn't Apple do something this bold before? Apple board member William Campbell, CEO of Intuit, says the answer is simple: "They didn't have Steve." Jobs is for once uncharacteristically modest. "A crisis," he says with a shrug, "is a wonderful time to make some changes...
...side effects will prove to be an illusion. All the enzymes and growth-factor receptors blocked by the new drugs play a role in normal cell division as well as in cancer. So disrupting them could cause harm. "Whether the therapy is going to be a major advance, a modest improvement or a disappointment is not clear," says Dr. J. Michael Bishop, molecular biologist at the University of California, San Francisco, who shared a 1989 Nobel Prize with Dr. Harold Varmus for their pioneering work on oncogenes. But Bishop is impressed that the field is moving so swiftly, and most...
...most excited by rhythmic ideas; the tunes are Latin standards from Puerto Rico, Cuba and Brazil, and Sanchez delights in reversing field on them, turning a gentle Antonio Carlos Jobim song, for instance, into a rowdy Caribbean parade. The album really soars when the accompanying 10-piece orchestra forgoes modest backing and muscles its way into the dance along with the congas. It's the kind of witty arranging that could give strings a good name...
...drugs that work in lab animals turn out to be duds in humans. The field is littered with "magic bullets" that failed, among them monoclonal antibodies, tumor necrosis factor, interferon and interleukin-2. While all were initially hyped as potential cure-alls, they have turned out to have only modest usefulness in the war on cancer. At best, says Dr. Allen Oliff, Merck & Co.'s chief of cancer research, no more than 10% or 20% of agents tried in mice succeed. (On the other hand, the treatments that are good for people are almost always good for mice...
...studios sensibly scale down. Troubled Universal's modest non-Hulk slate now includes the biotech scare show Virus, the George Clooney caper Out of Sight and Terry Gilliam's dopester saga Fear and Loathing in Las Vegas, with Johnny Depp--not just an anti-summer summer movie but an anti-Hollywood Hollywood movie...