Word: molecular
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Dates: during 1950-1959
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ACTH, expensively extracted from the pituitary glands of cattle, also helps many a disease, such as arthritis, but the magic compound, unfortunately, is anything but simple. It is a polypeptide, a large molecule (molecular weight 4,500) made up of many amino-acid units arranged in a long chain. Chemists have puzzled over its structure for years, but have learned only bits and scraps about it. Polypeptides (related to proteins) are baffling things to deal with...
Last week the University of California announced that a team led by China-born Dr. C. H. Li has determined the complete molecular structure of ACTH. It turns out to be a straight chain of 39 amino acids arranged in a definite order. After satisfying themselves about the position of each link in the chain, Dr. Li and his teammates broke the chain in two, separating 28 of the links from the remaining eleven. The larger section proved to have all the desirable biological effects of the whole natural molecule. Better still, it lacks certain bad side effects...
...modern theory of chemical-reaction rates. Richard Badger's rule described the relationship between the vibration and size of two-atom molecules. Through his work on the red and yellow pigments of such plants as carrots and tomatoes, Laszlo Zechmeister has determined some of the molecular configurations that are effective precursors of vitamin...
...there were plenty of diversions: the rushing by the four houses, the subsequent indignities after getting in (coolie hats, false noses, etc.), adjustment to the fact that class attendance is optional and that exams are run by the honor system. But there were also other matters-e.g., calculus, molecular physics, basic graphics, inorganic chemistry, as well as a big dose of English literature and European history. Though careful not to appear to be "snakes" (grinds). Supple and Andelin found themselves working a straight 80-hour week. Says Supple: "That first term you don't know where...
Pauling, Director of the Gates and Grellin Laboratories at the California Institute of Technology, will lecture under the general topic: "Molecular Structure and Biological Activity...