Word: molecular
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Dates: during 1970-1979
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...within cells in small granules called ribosomes. But ribosomes are themselves highly complex protein structures that obviously evolved long after protein first appeared. Then how, without the complex ribosome "factories," was primitive protein produced? Last week, in a report published in the journal Origin of Life, a team of molecular biologists suggested an answer. If the hypothesis is correct, says one of the researchers, it could alter Darwin's theory of natural selection and current concepts of genetic engineering...
Updating Darwin. Pieczenik believes there is further significance in the DNA patterns he discovered. In his view, the constraints suggest that a process of natural selection occurs at the molecular level long before organisms develop. If this is true, some additions will have to be made to the Darwinian theory that natural selection takes place only after the organism is formed and begins adapting to the world around it. That notion does not seem to bother Pieczenik. "What this means," he says, "is that the DNA sequences exist to protect themselves and their own information...
...invited Ruth Hubbard '44, lecturer on Biology, Bernard D. Davis '36, Lehman Professor of Bacterial Physiology at the Med School. Matthew S. Meselson, chairman of the Department of Biochemistry and Molecular Biology, and Jonathan R. Beckwith '57, professor of Microbiology and Molecular Genetics at the Med School, to speak at the three-day conference...
While determining the entire 5375 nucleotide sequence which determines the genetic make-up of the virus Phi-X174, the group at the Laboratory of Molecular Biology in Cambridge, England found that the same portions of the sequence could be 'read' in two different ways, each leading to the synthesis of a different protein...
Stroke's process, developed under a grant from the National Science Foundation, promises to make molecular structures visible. Stroke had been experimenting since 1963 with new ways to utilize holography. But it was not until about a year ago that he and his colleagues-Maurice Halioua, Venugopal Srinivasan and Raghupathy Sarma-hit upon their potentially revolutionary process. Explains Stroke: "We realized that a crystal, in which the atoms are arranged in a repeating array, can be made to produce a sort of hologram, a three-dimensional display of data. What we've figured...