Word: molecular
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What doctors suspect is that both leptin and ghrelin are part of a complex system of brain and body chemicals that have evolved over millions of years to govern weight and appetite. Says Dr. Rudy Leibel, an obesity expert and head of the molecular-genetics department at Columbia University: "It's just unlikely that any single component of this system will necessarily lead to a definitive therapeutic agent...
...Scientific Pole." The CIGB alone takes up some more than 120,000 square feet, mostly full of gray, monolithic Soviet-era buildings, but laid out in a campus style reminiscent of U.S. software firms. Some of the hemisphere's most advanced research in pharmaceuticals, immunology, mammal cell genetics, plant molecular biology and even plant cloning and transgenic experimentation is conducted at the CIGB. The buildings are crammed with state-of-the-art equipment imported from Europe, Brazil and Japan. Visitors pass through myriad barriers that spray visitors, dressed in special suits, with a disinfectant mist. The CIGB, which...
...patients' interest. Our trials can never be too safe. But we should not lose sight of the fact that our system has given rise to spectacular advances in cancer therapy, including Gleevec for leukemia; the control of aids; treatments for breast cancer; and others. As a new era of molecular genetic research dawns, we need to make certain that the strides we make in devising new therapies are matched by progress in ensuring patient safety. FRANK G. HALUSKA, M.D., PH.D. Director, Melanoma Program Massachusetts General Hospital Boston
...they are raising, money is finally flowing into autism research, a field that five years ago appeared to be stuck in the stagnant backwaters of neuroscience. Today dozens of scientists are racing to identify the genes linked to autism. Just last month, in a series of articles published by Molecular Psychiatry, scientists from the U.S., Britain, Italy and France reported that they are beginning to make significant progress...
...many genes contribute to susceptibility to autism? Present estimates run from as few as three to more than 20. Coming under intensifying scrutiny, as the papers published by Molecular Psychiatry indicate, are genes that regulate the action of three powerful neurotransmitters: glutamate, which is intimately involved in learning and memory, and serotonin and gamma-aminobutiric acid (GABA), which have been implicated in obsessive-compulsive behavior, anxiety and depression...