Word: molecular
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...play vital roles in other aspects of cellular metabolism, so that interfering with them will come at the price of serious side effects. For another, it is still far from proven that beta amyloid is as central to Alzheimer's disease as, say, cholesterol is to heart disease. Says molecular neurologist Dr. Peter St. George-Hyslop of the University of Toronto: "We have a theory and experimental data that support that theory, but we won't know the theory is right until we have a drug that actually prevents Alzheimer's disease...
Once activated, the T cell becomes a sort of commander in chief of immunity, activating the B cell--which secretes antibodies--and prompting the release of a farrago of inflammatory molecular signals...
...real hopes for the long term are pinned to molecular biologists; they are best equipped to identify targets unique to fungi and to design drugs that will attack them and them alone. Tiny biotech companies and huge pharmaceutical firms alike are working on drugs that will kill off fungi by preventing enzymes from binding to DNA or by halting protein synthesis...
...medicine chest (a process that can take as long as 15 years). But the odds are better now than when tranquilizers came largely from inspired guesswork. Computerized brain scans, DNA probes and other technological wizardry have given drugmakers powerful new tools for understanding at a molecular level the brain's inner workings--and how chemicals affect them...
...genetics of weight regulation--and how the whole system can go awry. With that understanding, they believe, it may be possible to develop drugs that do the job balky genes fail to do--controlling a problem that decades of fad diets and self-help books have never solved. Says molecular biologist Jeffrey Friedman of the Howard Hughes Medical Institute at Rockefeller University in New York City: "Genomics will identify the players in this system, eventually leading to new targets and new treatments...