Word: monilia
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Dates: during 1950-1959
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...trying the test diets he suggested. They had to admit that Ohishi was right: starches were bad for him, and bread was the worst. Dr. Tsuneo Takada, 30, took samples of Ohishi's digestive juices. In them microbiologists found a flourishing growth of a yeastlike fungus, Candida (or Monilia) albicans, occasional cause of human infections, but usually in the mouth or the vagina. In a normal gut, Candida may occur without causing fermentation. But in Ohishi's repaired bowel there was a little pocket where the Candida hid, multiplied, and busily fermented carbohydrates to form alcohol...
...justified: 1) streptomycin with other drugs (such as isoniazid) to discourage the appearance of resistant tubercle bacilli; 2) penicillin with streptomycin for inflammation of the heart lining (endocarditis); 3) tetracycline (or related antibiotics) with nystatin, not routinely but in some cases, to guard against secondary infection with the fungus monilia. Granting exceptions such as these, the Archives' editorialists conclude: "It is our firm conviction that the promotion and sale of such combinations should be discouraged...
...intestine is not the only organ troubled by the Monilia fungus. This microorganism was first found in the throat (in cases of thrush), also occurs regularly in the vagina. Many women who take aureomycin or related antibiotics develop a stubborn inflammation of the vagina and perineal region. Sometimes the organism spreads over large areas and reaches the lungs or brain heart or kidneys. There have been cases in which a child's entire body has been covered with itchy inflammation. In treating such cases of moniliasis, still another antibiotic has been found to help undo the harm wrought...
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