Word: motes
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...been learned so far about ACTH's awesome power to change the innermost workings of the body was published last week in a single volume, Clinical ACTH (Blakiston; $6.50). Normally it would have taken years for 52 such reports to seep into scattered medical journals. Dr. John R. Mote, director of the Armour Laboratories, which produce most of the world's pitifully small supply of ACTH, collected the papers, with 421 illustrations, so that researchers could have all the available data in one package...
After tests on 53 normal people and 560 patients suffering from 72 diseases and disorders, there was no doubt of ACTH's dramatic powers. It can interrupt many diseases which have baffled doctors for centuries. But the way it works is no less baffling. Says Dr. Mote: his collection of data will raise many more questions than it answers. Its chief significance lies not in promises of quick cures by ACTH itself, but in giving clues to how the body works in health and disease, so that cures may eventually be found...
Because of ACTH's power to turn certain disease processes off & on at will, Dr. Mote believes that its discovery compares in importance with the identification of bacteria as causes of disease. After a century, the full bacteria story is not yet known. It may take as long to unravel the mysteries of such hormones as ACTH...
Touted Wide. Medical researchers and big, blond Dr. John R. Mote, head of Armour Laboratories, would be happier if publicity on ACTH could have been delayed until their work was farther advanced. But the results of the first experimental treatments were too good to be withheld. The laboratories and clinics known to be using ACTH experimentally were bombarded with unanswerable requests from arthritis sufferers for a supply of the drug...
Armour is conducting its own research in the hope of increasing the supply, said Mote. If the complex structure of the ACTH molecule can be determined, he hopes to be able to stop making it in minute quantities from hogs' heads, and start to synthesize it by the hogshead. Until then, the millions of sarthritics and the countless sufferers from gout and a dozen other diseases must live in hope...