Word: motores
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Dates: during 2000-2009
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...Kevin Eggan at the Harvard Stem Cell Institute and Christopher Henderson at Columbia University, the 13-person team reported online today in Science Express that they had generated motor neurons from the skin cells of two elderly patients with a rare form of ALS, or Lou Gehrig's disease, a progressive neurodegenerative condition. The new study marks an important first step on the road toward real stem-cell-based therapies, and also answers several plaguing questions about the pioneering stem-cell technique known as induced pluripotent stem cell, or iPS, generation...
...Eggan's group has successfully turned stem cells into motor neurons, the cells that connect the spinal cord to the body's muscles and which degenerate in ALS. But researchers have not been able to prove that these cells will be clinically useful - that is, whether the new nerve cells will work as well as healthy ones in the spinal cord of a patient. Testing the viability of cells made from iPS stem cells is still a long way off, mostly because iPS requires the use of viruses to deliver the time-reversing genes into adult cells - that works...
...theory about the cause of ALS is that motor nerves die after exposure to a toxic compound released by other nerve cells in the spinal cord. The Harvard and Columbia groups are hoping to test that idea in the lab: if the cells in culture release the same agent, then finding drug compounds that block the damaging effects of the toxin could preserve neurons and hold off the paralyzing effects of the disease...
...models show that green can be given a devastatingly cool makeover. Britain's Lightning GT and the U.S.-built Tesla Roadster both reach 60 m.p.h. in 4 seconds or less, their makers claim, with top speeds approaching 130 m.p.h. The Lightning GT - unveiled at London's International Motor Show last week and set to be available from the end of 2009 - sports an impressive, sleek and sexy design, drawing on Aston Martin's classic British look. Tesla, which launched its hot, little open-top two-seater a couple of years ago, has already sold out of the 2008 model...
...London High Court judge has ordered British tabloid News of the World to pay $120,000 in damages to motor-racing chief Max Mosley following a weeklong court hearing involving frank discussions of prostitution, sadomasochism and "Nazi"-fueled...