Word: muscularly
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Science has made a giant step towards finding the cure for muscular dystrophy, MIT researchers said yesterday...
...Mendel gleaned from his painstaking studies of garden peas. One of the most strongly held beliefs has been that genes -- whether normal or abnormal -- are passed from generation to generation essentially unchanged. Now that assumption is being challenged. Last week scientists announced that in people with a form of muscular dystrophy, they had identified a segment of DNA that can lengthen substantially with each succeeding generation. Most disturbing, as the fragment lengthens, the illness becomes more severe. "This is not your garden-variety genetic defect," says Dr. Leon Charash, who chairs the medical advisory committee of the Muscular Dystrophy Association...
...startling discovery, reported in Nature by an international trio of research teams, marks only the third time such a genetic phenomenon has been found. Last year researchers revealed a similar process in two much rarer inherited diseases: fragile X syndrome, a form of mental retardation; and spinal and bulbar muscular atrophy, a wasting disease...
...myotonic dystrophy, the most common form of muscular dystrophy, the change can be far from negligible: a fragment of DNA on chromosome 19 appears to repeat itself more frequently with every generation. Just what triggers the repetition is a mystery. Researchers surmise that a hitch occurs while DNA is being copied in the cell, much as the same bar of music repeats on a scratched record. The DNA repeat gets worse with each generation, just as with each playing of a flawed record, the music stutters for a longer period. "Presumably the replication error occurs in the sperm...
...Vide. The three muscular men who make up Right Said Fred objectify themselves in the most beautiful of ways. They strut, they preen, they flex, they "shake their little tushes on the catwalk." Delicious...