Word: nabel
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Dates: during 1990-1999
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...vectors may not have to be viruses. Some researchers are working on ways to inject DNA directly into human cells. To treat patients with malignant melanoma, a deadly skin cancer, a team led by Dr. Gary Nabel at the University of Michigan encased a tumor-fighting gene in liposomes, harmless little bubbles of fat. The genes found their way into the proper cells, and in at least one case the tumors shrank...
...Michigan's Dr. Gary Nabel, the researchers treated five patients with melanoma, a deadly skin cancer. The tumors were injected with the gene HLA-B7, which produces a protein that can help the immune system fight the cancer. In all five patients, the genes safely entered the tumor cells and began making protein, and in one case the tumors shrank. The technique is no miracle cure, but the experiment adds a promising new weapon to the arsenal of genetic medicine...