Word: nasality
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BOSTON--Sedated and sand-bagged, a large gray-and-white dog named Poochie lies motionless on a gurney. His mouth is wedged open to allow the linear accelerator above his head to aim radiation directly at the malignant tumor blocking his nasal passages...
...million albums--country music's one bona fide superstar. Sevens sold about 800,000 copies the first week, and it's not just his bosses at Capitol Records who hope Brooks keeps moving the product. Country needs a hit. Country needs...something. Like a lonesome cowpoke in some nasal old lament, it feels the redneck blues...
Cold viruses have had millions of years to evolve different ways of infecting the cells that line the nasal passages. (The "rhino" of rhinoviruses comes from the Greek word for nose.) But it turns out that almost all the rhinoviruses use the same molecular doorway on the surface of the cell, a protein called ICAM-1, to gain entry to the upper-respiratory tract. Doctors have suspected since the late 1980s that if they could somehow flood the nose with decoy ICAM-1 molecules, they might be able to keep the rhinoviruses from attaching to the real thing...
...volunteers who were willing to catch a cold for science. Half the volunteers (the experimental group) were sprayed with the BIRR 4 solution. The others (the control group) were given a simple saline spray. All the volunteers were deliberately infected by placing droplets of active rhinoviruses in their nasal passages...
...intractable. For example, clival chordomas, deadly tumors that grow at the base of the skull, could be reached only by cutting through the entire brain, which left patients devastated. As one of the pioneers of skull-base surgery, Black now removes clival chordomas by going up through the nasal passage, bypassing the brain entirely. His patients go home without any loss of function (known to doctors as a "deficit...