Word: nausea
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...places to treat morning sickness. In the new study, the largest one of maternal metoclopramide use to date, involving nearly 3,500 babies born between 1998 and 2007 in a region in southern Israel, the rate of congenital birth defects in babies born to mothers who used the anti-nausea drug was about the same as that in babies whose mothers had not (5.3% vs. 4.9%). What's more, the length of time pregnant women used the drug appeared to not affect the rate of abnormalities in their babies: 4.9% of women who took metoclopramide for up to one week...
...despite the pervasiveness of pregnancy-related nausea, there is still no easy treatment, since most expecting mothers and their doctors aren't keen on exposing a still developing fetus to medications. Now, researchers from Israel and Canada report in the New England Journal of Medicine that a commonly prescribed heartburn drug, which also has anti-nausea properties, may be used in pregnant women without causing harm to babies. (See safety issues about taking pills during pregnancy...
Until now, there have been only about half a dozen studies looking at metoclopramide as a treatment for morning sickness. Even taken together, these studies include only about 500 babies. Because of the paucity of data, most doctors have prescribed the drug for nausea infrequently and only as a last resort - for instance, in cases where nausea and vomiting are so severe that a woman cannot function. Most mothers-to-be in the U.S. are given antihistamines instead, which help calm queasiness with few lasting effects on the fetus; the only downside for moms is side effects like drowsiness. (Read...
...before that can happen, he warns, more studies need to be done on how well metoclopramide actually controls nausea. At the moment, the drug, which calms digestive activity by slowing the contraction of intestinal muscles, is approved by the FDA only for the treatment of heartburn and other intestinal disorders. The drug's mechanism is believed to combat nausea by relieving the spasms that prompt queasiness. "What happens when people vomit or feel nauseous is that everything is stopped up," says Koren. "Metoclopramide helps move things forward and does not cause sedation like antihistamines...
...Some economists see a recovery by the beginning of the fall and others see it coming early in 2010. There is a near certainty that the nausea inducing drop from the fourth quarter of last year through March is over. It is either over because of the economy's natural resilience or the money poured into the economic system by the Fed and other central banks. Before anyone figures out for sure why things have started to improve, it will be too late to matter for anyone other than the historians. There will be another financial and market catastrophe...