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Dates: during 2000-2009
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...month trial involving 107 patients, the physicians showed that streptomycin curbed the number of deaths from TB. That success was short-lived: the TB bacilli quickly became resistant to the drug, blossoming into raging infections. Crofton, however, had the insight to combine streptomycin with another new antibiotic--a formula that was to become the blueprint for combination therapy. That approach still forms the cornerstone of TB treatment and served as the inspiration for similar multipronged attacks on serious illnesses, like treating cancer with chemotherapy agents and battling HIV with antiviral drugs...

Author: /time Magazine | Title: Sir John Crofton | 11/23/2009 | See Source »

...goofy, he can do suave, and in dramas like Syriana, for which he won an Oscar, he can seem close to emotional exhaustion. Up in the Air, which has already been named the year's best film by the National Board of Review, takes him in a new direction, one that may be closer to his core: a self-sufficient man who doesn't want to be tied down. His Ryan Bingham is a management consultant hired by the bosses at large companies to tell their employees they're no longer employed. And he does so with such ostensible sympathy...

Author: /time Magazine | Title: Clooneypalooza: A Star Is Airborne | 11/23/2009 | See Source »

Everybody knows where the story ends up. Meyer has sold 45 million books in the U.S. and 40 million more worldwide. Altogether her books have spent 235 weeks on the New York Times best-seller list, 136 of them at No. 1. The movie version of Twilight, which came out a year ago, made $350 million. New Moon opens on Nov. 20; the third installment, Eclipse, arrives in theaters next June. (See portraits of characters from New Moon...

Author: /time Magazine | Title: It's Twilight in America: The Vampire Saga | 11/23/2009 | See Source »

...New Moon was published on Sept. 6, 2006, less than a year after Twilight. Little, Brown printed 100,000 copies, a modest increase, but the company quickly realized something had changed. Advance copies were popping up on eBay for hundreds of dollars. Meyer's readings were turning into mob scenes. "We were outside Philly at a suburban Barnes & Noble," Tingley says. "The kids had been cutting school to get these tickets and waiting in line forever. When Stephenie came out, these girls next to me started trembling and crying and grabbing each other. It was crazy ... it was like...

Author: /time Magazine | Title: It's Twilight in America: The Vampire Saga | 11/23/2009 | See Source »

...New Moon Rising But when it came time to film the sequel, Hardwicke balked. Summit was pushing hard to get the new movie done fast, to keep up the momentum, and she was burned out. Enter Chris Weitz, who was not, by his own admission, the obvious choice. "There was a reasonable amount of skepticism when I took over the second movie," he says. "I understand that. I directed American Pie. I would be worried too." But after a 2½-hour phone conversation with Meyer - a fan of Weitz's About a Boy - she gave him her blessing...

Author: /time Magazine | Title: It's Twilight in America: The Vampire Saga | 11/23/2009 | See Source »

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