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Dates: during 2010-2019
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Epigenetics brings both good news and bad. Bad news first: there's evidence that lifestyle choices like smoking and eating too much can change the epigenetic marks atop your DNA in ways that cause the genes for obesity to express themselves too strongly and the genes for longevity to express themselves too weakly. We all know that you can truncate your own life if you smoke or overeat, but it's becoming clear that those same bad behaviors can also predispose your kids - before they are even conceived - to disease and early death...
...good news: scientists are learning to manipulate epigenetic marks in the lab, which means they are developing drugs that treat illness simply by silencing bad genes and jump-starting good ones. In 2004 the Food and Drug Administration (FDA) approved an epigenetic drug for the first time. Azacitidine is used to treat patients with myelodysplastic syndromes (usually abbreviated, a bit oddly, to MDS), a group of rare and deadly blood malignancies. The drug uses epigenetic marks to dial down genes in blood precursor cells that have become overexpressed. According to Celgene Corp. - the Summit, N.J., company that makes azacitidine - people...
...added that Tripsas should not have been allowed to write about business from the start, as she teaches Harvard executive education classes customized for and paid by companies—a violation of the Times' policy banning commissions and assignments from news sources...
...Since the company pays Harvard and Harvard pays me, I would not have considered this a violation," Tripsas wrote, "but as one of the editors said to me in an e-mail, 'It was also news to me that executives were paying Harvard to have you train them. That—had it been disclosed to us in the beginning—would have precluded you doing the type of column for us that you are doing...
...never seen it like this," said Agne Kveslyte, a Lithuanian student. "They were opening up really tiny items I had, even my wallet." Once on the plane, passengers were not allowed to congregate near the lavatories or pass between different sections of the plane. (See the top 10 news stories...