Word: nih
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Dates: during 1950-1959
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...what she was looking for, but she got something better. Many of the mice she injected with Gross's "leukemia virus" got solid tumors, mainly in the parotid (salivary) glands. (Dr. Heller's theory: the Gross material had contained two viruses.) Dr. Stewart teamed with the NIH's Dr. Bernice E. Eddy to grow the solid-tumor virus in tissue cultures of monkey kidney cells (as polio virus is grown to make Salk vaccine...
Effective Drugs. Despite admitted drawbacks, chemotherapy has won a solid foothold. Dr. Charles Gordon Zubrod, 45, NCI's clinical director, responsible for all cancer patients treated in NIH's huge Clinical Center (TIME, July 20, 1953), . lists eight forms of the disease that can often be set back by drugs, sometimes for as long as two or three years. These are: acute leukemia in children, chronic lymphocytic and myeloid leukemia in adults, Hodgkin's disease, rhabdomyosarcoma (a rare muscle cancer), Wilms's tumor (in the kidney, present at birth), cancer of the adrenal glands, and choriocarcinoma...
...invaluable but dangerous derivative of the opium poppy. Last week Secretary Arthur Flemming of Health, Education and Welfare got himself out on a limb by announcing as "an exciting breakthrough" the development of a new analgesic at the National Institutes of Health. Known so far only as NIH 7519, it appears, he said, to have "painkilling power at least ten times that of morphine." (By this phrasing, scientists do not mean that it can kill pain ten times as severe as morphine does, but that it kills the same pain with one-tenth the dose.) At the same time, said...
Fact is that, so far, NIH 7519 has had such limited trials on human patients that doctors cannot be sure how potent a painkiller it is-or, consequently, what dose to give. Addiction dangers are directly related to continued use. Most of the hopeful evidence on addiction comes from monkeys; though tests are under way with narcotics addicts at the Public Health Service Addiction Research Center in Lexington, Ky., results are only preliminary...
...NIH 7519 has one undeniable advantage. Member of a chemical family called benzomorphans, it is entirely synthetic. If it proves as valuable a morphine substitute as Secretary Flemming hopes, it will free the U.S. of dependence on imported opium, which is becoming harder to get in world markets and might be cut off entirely in global...