Word: nih
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Dates: during 1960-1969
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...first month after delivery are among the 7% born prematurely. Some doctors, though, see no direct connection between smoking and prematurity; they argue that the problem is a matter of temperament, that high-strung women who smoke would have a high proportion of "preemies" anyway. To make sure, NIH's Dr. Richard Masland wants to check the same mothers before and after they quit smoking...
...design of the experiment is straightforward enough, and it might have been started earlier but for one drawback: there was no way to check on the women being tested to make sure that they did not sneak an occasional secret drag. Now NIH has found a chemical detective. Researchers at San Antonio's Southwest
...such a change. A pump sends a continuous infusion into an artery in each subject's left arm. In the infused fluid is an infinitesimal amount-1/90,000 oz. per day-of a mysterious and immensely potent substance called angiotensin. Explained Dr. Frederic C. Bartter, head of NIH's hormone studies: "We know that a lot of angiotensin raises the blood pressure and causes salt retention. What we need to know is whether an increase so small that it does not raise the blood pressure will nonetheless cause salt retention, and therefore help to account for edema...