Word: nih
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Dates: during 1970-1979
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Measurement of Forces Between and Within Lipd Membranes--Dr. V. Adrian Parsegian, NIH, Science Center...
...Detrick. Md. Next week it will become the site of an important experiment. Converted at a cost of $250,000, the facility has been certified by the National Institutes of Health as the nation's first P-4 laboratory, where the riskiest genetic research now permitted by the NIH can be conducted. The lab's initial test will attempt to answer two vital questions: Can recombinant DNA research create dangerous organisms? If so, can they be safely handled in a laboratory...
...first stage of the experiment, NIH'S Malcolm Martin and Wallace Rowe will splice DNA from the polyoma virus (which causes tumors in mice but not in humans) into a specially engineered strain of the common bacteria Escherichia coli. The bacteria will be fed to or injected into mice and hamsters, which will then be examined to determine 1) if the bacteria multiply into progeny that also contain the viral DNA, and 2) if the bacteria-carried viral DNA can cause tumors in the animals...
...experiments will also provide a good test of Building 550, which was designed to prevent material from recombinant DNA work from escaping into the environment. NIH officials are confident that the new lab is even more secure than the Lunar Receiving Laboratory, which was built by NASA at a time when it was still thought that astronauts might bring back dangerous bugs from the moon...
...genes of life to create a brave new world?" asked Jeremy Rifkin of the Peoples Business Commission. But many scientists who only a year ago opposed recombinant DNA research are now largely convinced that the hazards have been overstated. Besides, as Microbiologist John E. Nutter, manager of the NIH P-4 program, notes, "the potential benefits of being able to reproduce large quantities of genetic material are enormous...