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...late. By the time AD is diagnosed, too many brain cells may have died for the process to be reversed. "If we can come up with better diagnostic procedures, it might be possible to block the progress of AD chemotherapeutically in the next five years." says Gibbs of NIH One promising method is a new scanning process called PET (positron emission tomography), which measures glucose metabolism in living cells. PET-scan studies by Dr. David Kuhl of U.C.L.A., among others, have revealed drastic decreases in metabolism in the brains of AD patients. Kuhl hopes to develop an early diagnostic test...

Author: /time Magazine | Title: Medicine: Slow, Steady and Heartbreaking | 7/11/1983 | See Source »

Nevertheless, Heckler stressed to the patients that "AIDS is our No. 1 health concern and the epidemic is our No. 1 priority." Her department, which includes CDC and NIH, is spending $14 million on AIDS research this year and requesting $12 million more. Some gay activists have charged that the Reagan Administration is neglecting AIDS because it primarily affects homosexuals. (In fact, the money allocated to AIDS research so far is greater than the $20 million spent over eight years on toxic shock syndrome and Legionnaire's disease.) Heckler's department also publishes a biweekly bulletin reporting the findings...

Author: /time Magazine | Title: Hunting for the Hidden Killers: AIDS | 7/4/1983 | See Source »

Those medical-mystery solvers include general practitioners and specialists who become involved in a particular case because it affects their patients. Others can be found among the nation's state and local public health officers. Researchers at the NIH supply scientific support. Coordinating this network, and indeed serving as the FBI of disease detection and the Interpol for medical sleuths around the globe, are the 4,030 workers at the CDC. The vanguard of this organization is the center's Epidemic Intelligence Service (EIS), which sends out its corps of 120 young, bright and determined investigators around...

Author: /time Magazine | Title: Hunting for the Hidden Killers: AIDS | 7/4/1983 | See Source »

Based on what is known so far, two theories have emerged. One is that AIDS is caused by a specific agent, most probably a virus. "The infectious-agent hypothesis is much stronger than it was months ago," says Curran, reflecting the prevailing opinion at CDC. NIH Researcher Fauci, who staunchly believes that the culprit is a virus, has been collecting helper T-cells from AIDS victims to look for bits of viruses within their genetic codes. So far, however, this and other complex methods of detecting viruses have yielded nothing conclusive. Suspicion focuses on two viruses: one is a member...

Author: /time Magazine | Title: Hunting for the Hidden Killers: AIDS | 7/4/1983 | See Source »

...cure is in sight. But the research already has benefited some patients. New knowledge about the immune system has inspired doctors to be more careful when treating Kaposi's to use therapies that do not lead to further suppression of the immune system. Fauci of NIH has conducted a bone marrow transplant that bolsters a patient's immune system. Along with many other researchers, he is testing the effects on AIDS patients of new forms of interferon, a component of the human immune system that can now be reproduced by genetic engineering...

Author: /time Magazine | Title: Hunting for the Hidden Killers: AIDS | 7/4/1983 | See Source »

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