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...CHOP along with scientists at numerous other institutions, looked at a specific kind of genetic change: deletions and duplications of genes. While there are many such changes associated with autism, most are very rare. This paper, however, found an intriguing pattern among two genes already linked to autism and nine newly identified targets. Most play a role in two key systems in the brain. One is the same brain-wiring system - neural cell adhesion - implicated in the first paper. The second is a set of housekeeping proteins - the ubiquitin system - that whisk away old brain connections and set the stage...

Author: /time Magazine | Title: Autism Linked to Genes That Govern How the Brain Is Wired | 4/28/2009 | See Source »

...relationship between record companies and reissue buyers has not historically been built on good faith. Anyone who owns one of the nine versions of the Beach Boys' Pet Sounds, each with its own seductive "extra" features, knows it's a lot more like the relationship between Charlie Brown and Lucy. But after years of selling slightly improved old goods at steep new prices, at least a few labels have started focusing on quality control. "In this day and age and economy, we have to make something remarkable, or we're not going to be able to compete," says Adam Block...

Author: /time Magazine | Title: Old Music, New Package: Will You Buy It — Again? | 4/27/2009 | See Source »

...Change Is Causing a New Age of Extinction," but the article does not--and cannot--say that. Climate change is mentioned only in passing, and the major causes of extinction are clearly shown to be deforestation and encroachment on habitat. The pictures in "10 Species on the Brink" show nine truly endangered species, then throw in the polar bear, which is 10 times as numerous as any other animal depicted, to try to make the climate-change link. An otherwise fine issue on extinction is thus marred by a gratuitous climate-change reference that is inapplicable and misleading...

Author: /time Magazine | Title: Inbox | 4/27/2009 | See Source »

Supplying fibers to so many different markets means the company is not reliant on any one segment for survival. Patrick has made production evolution and new designs the key components of his business model. Patrick Yarns holds nine patents and six trademarks in engineered yarns and those used for filtration. Natural fibers such as cotton and hemp end up in blankets and upholstery. Synthetic yarns have a variety of commercial uses, including in water filtration, as carpet backing and for automotive fan belts. The technical yarns developed from stainless steel, glass or Teflon find their way into fiber-optic cables...

Author: /time Magazine | Title: Spinning a New Strategy | 4/27/2009 | See Source »

...After returning eight of nine position starters from last year’s Ivy North championship team, and still carrying nine players who had won the Ancient Eight title in 2007, Harvard looked to be the odds-on favorite to get back to the ILCS and avenge last season’s sweep at the hands of Princeton...

Author: By Kate Leist, CRIMSON STAFF WRITER | Title: TO SAY THE LEIST: Harvard Can't Come Up With Final Rally | 4/27/2009 | See Source »

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