Word: nishihara
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Dates: during 1960-1969
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...Tails. X-ray studies reveal natural collagen as three strands of molecules twisted together like rope. The strands are short, and many have to be joined end to end to make up the body's long collagen fibers. Dr. Tomio Nishihara, a physical chemist who heads research for the Japan Leather Co., and Dr. Francis O. Schmitt of the Massachusetts Institute of Technology, thought there must be something on the ends of the basic molecules that enabled them to couple. Dr. Albert L. Rubin and an M.I.T. team set about testing the theory. They found that each collagen strand...
...reconstituted collagen, the Japan Leather Co. uses odds and ends of calf skin left over when the hides have been cut for making shoes. After weeks of soaking and washing hide in various chemicals, including enzymes, to remove the linkage tails, Dr. Nishihara pours collagen into thin sheets resembling cellophane. The resulting membrane makes fine, easily digestible sausage casing. It also gave the Rogosin Labs' Dr. Rubin and Dr. Kurt Stenzel an idea for its first medical application-use in the artificial kidney, which has a filter membrane of sausage-casing cellophane. In laboratory glassware the collagen membrane...