Word: non-hodgkin
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...critics or slowing the biopharmers. Open-air trials of pharmaceutical crops have taken place in 14 states, from Hawaii to Maryland. A Texas firm is selling a corn-bred enzyme that stimulates insulin production in diabetics. Clinical trials have begun for experimental crop-grown drugs to treat cystic fibrosis, non-Hodgkin's lymphoma and hepatitis B. "Molecular farming represents the pharmaceutical industry's best opportunity to strike a serious blow against such global diseases as AIDS, Alzheimer's and cancer," says Francois Arcand, president of the Conference on Plant-Made Pharmaceuticals, held in Quebec City earlier this year...
...Scientists had learned over the years that cancer cells are studded with an unusually large number of receptacles that compounds essential for survival, including growth factors, can plug into and fuel the cells' growth. Rituximab is a monoclonal antibody, a molecule specifically engineered to fit into the receptacles on non-Hodgkin's lymphoma cells and, in this case, single out the cancer cell for destruction by the immune system. Back in the early 1980s, monoclonal antibodies were hyped in the media as "magic bullets" that would wipe out cancer...
...Scientists had learned over the years that cancer cells are studded with an unusually large number of receptacles that compounds essential for survival, including growth factors, can plug into and fuel the cells' growth. Rituxan is a monoclonal antibody, a molecule specifically engineered to fit into the receptacles on non-Hodgkin's lymphoma cells and, in this case, single out the cancer cell for destruction by the immune system. Back in the early 1980s, monoclonal antibodies were hyped in the media as "magic bullets" that would wipe out cancer...
...care for him full time, he had a circle of close friends that included a couple of nurses, one of them a bereavement counselor; an ethicist who specialized in medical issues; several doctors; and a former patient, Steve Kalafer, who years earlier had been treated by Frimmer for non-Hodgkin's lymphoma, now in remission...
...years now, "smart" drugs have been the hottest trend in cancer treatment. They are designed to zero in on the proteins that nurture tumor cells. In the past year alone, the FDA has approved three such drugs (for non-Hodgkin's lymphoma, breast cancer and leukemia). And more are in the pipeline, because scientists are becoming increasingly skilled at designing drugs that target specific, critical molecular processes that tumor cells need to survive. Herceptin, for example, takes advantage of the fact that most breast-cancer cells overproduce a certain growth-factor protein; the drug preferentially seeks out tumor cells...