Word: normal
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...suffer when rates rise. Still, after so many years trapped in an economic twilight zone, the Japanese may find such worries almost a pleasure to contemplate. As Tatsushi Shikano, a senior economist at Mitsubishi UFJ Research and Consulting, says: "It's a sign that things are going back to normal...
...reasons there was so much interest in a study that appeared last week in the Journal of the American Medical Association (J.A.M.A.) about the health effects of carrying around all those extra pounds. Researchers looked at health data from more than 90,000 older women--some of normal weight, some obese and some morbidly obese. They found over the course of the seven-year study that for white women, being obese rather than of normal weight was linked to a 12% greater risk of dying. Women who were at least 100 lbs. overweight, however, had an 86% greater risk...
Most of the errors in reprogramming, scientists say, can be traced to a process known as DNA methylation. During normal development, molecules called methyl groups attach themselves to DNA in precisely timed patterns that regulate which genes are expressed at which times. During cloning, however, those patterns are not always reconstructed in exactly the same way. It's a bit like taking all the words in a novel, jumbling them up and then trying to re-create the original book, putting sentences, pages and chapters back in the right order. The chances of that happening with 100% accuracy are minuscule...
...baby lamb. We will never know, though, whether her shortened telomeres would have shortened her life. In 2003 Wilmut and his team decided to put Dolly to sleep after she developed lung cancer caused by a viral infection common among sheep. An autopsy revealed that she was otherwise normal...
...studies of the faults introduced by reprogramming, Jaenisch, for one, thinks human cloning is now out of the question. "I think we cannot make human reproductive cloning safe," he says. "And it's not a technological issue. It's a biological barrier. The pattern of methylation of a normal embryo cannot be re-created consistently in cloning...