Word: normale
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Dates: during 1960-1969
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...They first had to regularize the woman's cycle, and they hit upon a synthetic progestin chemically akin to another female sex hormone, progesterone. The progestin, taken for 20 days in mid-menstrual cycle, suppressed ovulation by simulating pregnancy. Taken off the medicine, the women had a more normal cycle, with surer ovulation. After Pincus and Rock had produced a gratifying number of conceptions, a new idea struck them: Why not use the progestin deliberately to suppress ovulation every month-in other words, as a contraceptive...
...first the drug worked well. Several days after a woman stopped taking it, she had what seemed like a normal but mild menstrual period. There were few side effects. But as the drug was further purified, Dr. Rock began to hear patients complain of too much "breakthrough bleeding" in mid-cycle. Analysis showed that the purified drug contained no detectable estrogen. Apparently estrogen, even in the most minute quantity, prevented some side effects, including unwanted bleeding. So when Chicago's G. D. Searle & Co., which had worked closely with Pincus and Rock, began making "the Pincus pills" as Enovid...
Other hormone investigators took a different direction, concentrating on the rediscovered, though still not fully understood, powers of estrogen. From the fifth to the 20th day of a normal woman's cycle, her estrogen level is fairly steady, except for a dip at the time of ovulation. If they could prevent this dip, the researchers reasoned, they could prevent ovulation. They felt it would be more natural to do this by providing nothing but added estrogen until the 20th day, and then giving progestin only briefly. San Antonio Researcher Dr. Joseph W. Goldzieher worked with Syntex Laboratories to develop...
...selected opponent would not be told of the pass-fail designation, to ensure absolutely normal treatment of the G.U.T. less foe. The only change would be made by the sports registrar on the end-of-season won-lost record. The record would show that the team played such-and-such an opponent, but there would be no mention of the outcome...
...illustrations are inept. Joyce was half blind, and his Dublin is a city dimly seen but fantastically imagined. Strick's Dublin, however, is the ordinary place that shows up on postcards-even when Bloom sinks into parodic delusions of grandeur, the images in his fantasies remain invincibly normal and unexciting. The images, in effect, are afterthoughts; the film is essentially a book that several people are reading aloud...