Word: normale
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Dates: during 1990-1999
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...already closed for the school year. Father Kenneth Reinhart, who completes his term as Midwest superior of the Capuchins this week, stated, "We cannot undo the past, no matter how much we would like to. We can only help those who were injured to overcome their trauma and lead normal lives." He also pledged future reforms. Elliott, however, complained that the report gave no sense of the suffering young victims endured. Says Isely: "When the priest stole my body, he stole my childhood...
...first approved gene-therapy trials, the pioneering NIH team extracted immune-system T cells from the Ohio girls, inserted normal ada genes into the cells and reinjected them. As the team had hoped, the T cells began churning out natural ADA, enabling the children's immune systems to function effectively. While that result marked the first successful treatment by gene therapy, it was not a cure; the altered T cells die out after several months, and the little patients must return to the NIH periodically to repeat the procedure...
...latest experiment at the NIH, Blaese administered a drug to one of his two original Ohio patients that coaxed some stem cells out of the bone marrow and into her bloodstream. Extracting blood, he painstakingly separated out the rare stem cells, inserted normal ADA genes into their DNA and injected the cells back into the girl's bloodstream, hoping that they would migrate back to the marrow and take up permanent residence...
Although Richard and Lori Riggins, of Exeter, California, have a normal four-year-old daughter, a son born to them in 1991 was diagnosed with SCID at the age of four weeks, and ever since has required treatment with PEG-ADA to survive. His disorder was evidence that both his mother and father, while healthy themselves, carried a recessive gene for SCID. This meant that any of their offspring would have a 1-in-4 chance of being stricken with the disease. The outlook was equally gloomy for Crystal Emery and Leonard Gobea, from California's Imperial Valley; their first...
...part of the experiments. Immediately after Andrew was born, the obstetrician snipped his cord and drew out the umbilical blood. She rushed it to Childrens Hospital in Los Angeles, where a team led by Drs. Donald Kohn and Kenneth Weinberg separated the stem cells and endowed them with normal ADA genes. Then the newly equipped stem cells were injected into the baby's bloodstream. Two days later, Wara went through the procedure on Zachary Riggins in San Francisco, after his stem cells had been shuttled to Kohn and Weinberg in Los Angeles for genetic engineering...