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Lessing is a genuinely sui generis literary phenomenon, inexhaustible and defiantly unique - her oeuvre runs to over 40 books. Her principal theme is the experience of women in contemporary society, which she addressed most ambitiously, and successfully, in The Golden Notebook, her 12th novel, published in 1962. A formal tour de force, The Golden Notebook is the story of a divorced writer named Anna Wulf told through her four notebooks, each of which is concerned with recording a different aspect of herself. Brilliant, autobiographical and feverishly experimental, it's a bravura portrait of a shattered self, richly adorned with ruthless...

Author: /time Magazine | Title: Doris Lessing's Road to the Nobel | 10/11/2007 | See Source »

...ideologies, political or literary. She refuses to settle for simple answers or received wisdom, and she has never been afraid to commit heresy. In the 1970s she began experimenting with science fiction - it is unlikely that any other Nobel laureate could lay claim to a work like her 1994 novel The Making of the Representative for Planet 8, about an eco-catastrophe on a distant world. In August Lessing published a new novel, The Cleft, in which she re-imagines the history of the human race - originally, she proposes, humanity consisted entirely of women, all the trouble having begun when...

Author: /time Magazine | Title: Doris Lessing's Road to the Nobel | 10/11/2007 | See Source »

...their strict Edwardian mores and left school at 13 - that was the end of her formal education, although she continued to read voraciously. She left home at 15, moved to England and became associated with the Communist movement. Her writing career began in earnest in 1950 with her first novel, The Grass Is Singing...

Author: /time Magazine | Title: Doris Lessing's Road to the Nobel | 10/11/2007 | See Source »

...clerk and would watch, amazed, at how the location of a callus could reveal a man's profession, or how a quick look at a skin rash told Bell that the patient had once lived in Bermuda. In 1886, Conan Doyle - by now an eye doctor - outlined his first novel, A Study in Scarlet, which he described as "a simple tale of mystery to make a little extra money." Its main character, initially called Sherringford Hope and later rechristened Sherlock Holmes, was based largely on Bell. But Holmes' debut went almost unnoticed, and the struggling doctor devoted nearly...

Author: /time Magazine | Title: Mystery Man | 10/11/2007 | See Source »

...part of a growing trend in the search for vaccines against genetic diseases, including Alzheimer’s and Parkinson’s Diseases. Instead of inserting an active version of the harmful protein to stimulate a person’s immune response, as common vaccines do, this novel vaccine will directly introduce antibodies into the body that attack the mutated protein responsible for the disease. Lou Gehrig’s disease, technically known as amyotrophic lateral sclerosis (ALS), is a condition in which a mutated protein destroys motor neurons in the brain and spinal cord. Over...

Author: By Maeve T. Wang, CONTRIBUTING WRITER | Title: Profs Are Near Cure for ALS | 10/10/2007 | See Source »

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