Word: nucleic
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Dates: during 1970-1979
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Thursday, May 4: Chemistry Department Seminar: Dr. Karen Gennette on Benzo Pyrene Diol Epoxides as Intermediates in Nucleic Acid Binding In Zitro and In Vivo, Science Center...
Doctors have long suspected that viruses, submicroscopic packets of nucleic acids similar to the DNA found in chromosomes, play a role in human as well as animal cancers. Dr. Sol Spiegelman, director of the Institute of Cancer Research at New York Columbia-Presbyterian Medical Center and one of the world's leading cancer virologists, points out that virus-like particles can be found in just about every human cancer. But proving that these particles cause the cancers has been more difficult. The cases against several suspect viruses have had to be dismissed for lack of scientific proof. There...
...real origin of this concern was the discovery in 1953 at Cambridge University by Watson and Dr. Francis Crick that the pattern of all life forms is determined by a double-helical molecule of deoxyribonucleic acid, or DNA. Since then other investigators have found ways of cutting a long nucleic-acid molecule, by chemical means, into shorter pieces that can then be recombined...
...intimate association between even the most dissimilar organisms. For example, he points out that bacteria called rhizobia live in the roots of bean plants and enable them to utilize the nitrogen in the soil; without these parasites the plants would die. There are also viruses-small, independent packets of nucleic acids -which Thomas believes may have helped man evolve by transmitting bits of the master molecule DNA from one organism to another. Even the single cells that have combined to form a human being house microscopic non-human tenants whose value to the health of the cell appears unquestioned...
...There is new evidence that the main cancer villains are viruses, submicroscopic packets of nucleic acids that can invade cells and take over their genetic machinery. Using immunological techniques to identify antigens (the substances that trigger the body's defenses), Dr. Donald Morton of the University of California at Los Angeles has found signs of viral activity in human sarcomas, or cancers of connective tissue. Drs. Werner and Gertrude Henle of the University of Pennsylvania have studied an intruder known as the Epstein-Barr virus in cells from victims of Burkitt's lymphoma, a tumor of the lymph...